Regional and national
The Adult AIDS Clinical Trials Group, funded by the NIH, is the largest HIV clinical trails organization in the world. The ACTG plays a major role in setting standards of care for HIV infection and opportunistic diseases related to HIV/AIDS in the United States and the developing world. The UCSD AIDS Clinical Trials Unit is housed within the UCSD Antiviral Research Center (AVRC). From 300 to 350 subjects are followed at the AVRC in multiple ACTG trials at any given time.
The California Collaborative Treatment Group (CCTG) was founded in 1986 by J. , and currently co-directed by Richard Haubrich, MD, and investigators at UCLA and USC. The primary mission of the CCTG is to improve the scientific basis for HIV patient care and HIV prevention by improving treatment management and developing new ways to prevent transmission. CCTG studies at UCSD are managed by the UCSD Antiviral Research Center (AVRC).
The International Maternal, Child, and Adolescent AIDS Clinical Trials Group (IMPAACT) is funded by the NIH to conduct research on decreasing illness and deaths associated with HIV in pregnant women, children, and adolescents. IMPAACT represents a merger of two former NIH-funded groups: the Pediatric AIDS Clinical Trials Group (PACTG) and the Perinatal Scientific Working Group of the HIV Prevention Trials Network (HPTN/HIVNET). IMPAACT studies at UCSD are conducted by the Mother, Child, and Adolescent HIV Program.
The California NeuroAIDS Tissue Network (CNTN) is funded by the National Institute of Mental Health and directed by Igor Grant, MD. The CNTN collects, studies, and stores tissues from HIV-infected persons whose disease involves their central nervous system. CNTN studies at UCSD are managed by the HIV Neurobehavioral Research Center (HNRC).
The CNS HIV Antiretroviral Treatment Effects Research (CHARTER) study is funded by the National Institute of Mental Health and directed by Igor Grant, MD. The purpose of the CHARTER study is to evaluate the effects of antiretroviral drugs on the central nervous system of HIV-infected persons. CHARTER studies at UCSD are managed by the HIV Neurobehavioral Research Center (HNRC).
Studies of the Ocular Complications of AIDS (SOCA) is a nationwide research group funded by the National Eye Institute to study the effects of HIV on the eyes and vision. SOCA studies at UCSD are managed by the Shiley Eye Center.